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API 32-30236 1982

API 32-30236 1982-NOV-30 AN INHALATION TERATOLOGY STUDY IN RATS WITH MTBE

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INTRODUCTION

This study, conducted for the American Petroleum Institute, was designed to evaluate the embryotoxic and/or teratogenic potential of Methylt-butyl-Ether in the rat . The test substance was administered by the inhalation route at exposure levels of 250, 1000 and 2500 ppm. Test substance was administered 6 hours per day, daily from Day 6 to 15 of gestation, a 10-day period.

Species and strain of test animal, exposure levels and route of test substance administration were established by the sponsor. Testing was conducted at Bio/dynamics, Inc., Mettlers Road, East Millstone, New Jersey U8873, Raw data will be stored in the archives of Bio/dynamics Inc.